PgE2 treatment of oviducts

In the recent years, blocked oviducts have been recognized as an uncommon cause of infertility in the mare. Oviducts are thin tubes leading from the ovaries to the uterus and it is where the fertilisation of the egg by sperm takes place.

The oviducts of mares can become blocked by debris from previous ovulations or pregnancies. Blockage can lead to otherwise unexplained infertility. Mares can repeatedly fail to become pregnant to fertile stallions despite displaying no obvious abnormalities on veterinary examination.


Prostaglandin has a relaxation effect on the smooth muscle of the oviducts. This is used in the treatment of blocked oviducts where PgE2 is applied directly onto the oviducts during laparoscopy.